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The Ministry of Health’s Department of Disease Prevention has issued a notice warning that the HIV pre-exposure prophylaxis (PrEP) injectable drug YEZTUGO (lenacapavir) has not been registered or approved for sale in Vietnam, and that its origin is unclear, creating serious health risks for users.
The Department of Disease Prevention asked provincial health authorities to promptly inspect clinics, medical facilities, and pharmaceutical trading establishments to detect and address the sale and use of HIV PrEP medicines with unclear origins that have not been licensed for circulation.
Authorities were also instructed to strengthen communications and public warnings to medical facilities about the risks of counterfeit or unlicensed medicines.
Healthcare facilities were told to strictly follow prescribing rules for HIV PrEP medicines and to ensure that only products licensed by the Ministry of Health, with clear origins, are used. Prescribing, indications, and monitoring must comply with Decision 5968/QD-BYT of the Minister of Health on guidelines for the treatment and care of HIV/AIDS and related documents.
In late March 2026, the Drug Administration of Vietnam (DAV) warned about counterfeit medicines and illegally circulating injections of YEZTUGO. The DAV stated that an online check of information on the public service at https://dichvucong.dav.gov.vn/congbothuoc/index shows that it has not issued a circulation registration certificate for the product name or for the manufacturing facility.
The DAV said YEZTUGO injection (lenacapavir) 463.5 g/1.5 mL (309 mg/mL) has not been licensed for circulation in Vietnam.
The DAV asked provincial health departments to notify drug traders, users, and the public not to buy, sell, or use YEZTUGO (lenacapavir) injection 463.5 g/1.5 mL (309 mg/mL). It also requested that suspicious signs of counterfeit or unlicensed production or trade be promptly reported to health authorities and relevant agencies.
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